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Tal Kafri MD, PhD
Associate
Professor
MD/PhD Hebrew University, Jerusalem
919.843.7635
kafri@med.unc.edu
Research Interests: The development of lentivirus vectors for gene therapy, and on basic science of
HIV-1 biology.
Publications:
- Haack K, Adam SC, Ma H, Israeli D, Ho SN, McCown TJ, Kafri T. 2004. Transactivator and structurally optimized inducible lentiviral vectors. Molecular Therapy, 10(3):585-96.
- Logan AC, Haas DL, Kafri T, Kohn DB. 2004. Integrated self-inactivating lentiviral vectors produce full-length genome transcripts competent for encapsidation and integration. Journal of Virology, 78(16):8421-8436.
- Ma H, Kafri T. 2004. A single LTR HIV-1 vector optimized for functional genomics applications. Molecular Therapy, 10(1):139-149.
- Bahi A, Bover F, Kafri T, Dreyer JL. 2004. CD81-induced behavioural changes during chronic cocaine administration: in vivo gene delivery with lentivirus. Eur J Neurosci, 19(6):1621-33.
- Kafri T. 2004. Gene delivery by lentivirus vectors an overview. Methods Mol Biol, 246:367-90.
- Cockrell AS, Kafri T. 2003. HIV-1 vectors: fulfillment of expectations, further advancement, and still a way to go. Curr HIV research, 1(4):419-39.
- Hershko AY, Kafri T, Fainsod A, Razin A. 2003. Methylation of HoxA5 and HoxB5 and its relevance to expression during mouse development. Gene, 302(1-2):65-72.
- Vacek MM, Ma H, Gemignani F, Lacerra G, Kafri T, Kole R. 2003. High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA. Blood, 101(1):104-111.
- Pan D, Gunther R, Duan W, Wendell S, Kaemmerer W, Kafri T, Verma IM, Whitley CB. 2002. Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow. Molecular Therapy, 6(1):19-29.
- Kafri T. 2001. Lentivirus vectors: difficulties and hopes before clinical trials. Current Opinions Molecular Therapy, 3(4):316-26.
- Xu K, Ma H, McCown, TJ, Verma IM, Kafri T. 2001. Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Molecular Therapy 3(1):97-104.
- Kafri T, van Praag H, Gage FH, Verma IM. 2000. Lentiviral vectors: regulated gene expression. Molecular Therapy, 1(6):516-21.
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